ARG55555

anti-Annexin A1 antibody

anti-Annexin A1 antibody for Western blot and Human

Signaling Transduction antibody

Overview

Product Description Mouse Monoclonal antibody recognizes Annexin A1
Tested Reactivity Hu
Tested Application WB
Host Mouse
Clonality Monoclonal
Clone 794CT2.2.1
Isotype IgG1
Target Name Annexin A1
Antigen Species Human
Immunogen Purified His-tagged Human Annexin A1 protein.
Conjugation Un-conjugated
Alternate Names ANX1; Calpactin II; Phospholipase A2 inhibitory protein; Chromobindin-9; LPC1; Annexin-1; Annexin A1; Lipocortin I; Annexin I; p35; Calpactin-2

Application Instructions

Application Suggestion
Tested Application Dilution
WB1:1000 - 1:8000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control HeLa

Properties

Form Liquid
Buffer Crude Ascites and 0.09% (W/V) Sodium azide
Preservative 0.09% (W/V) Sodium azide
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 301 Human ANXA1

Swiss-port # P04083 Human Annexin A1

Gene Symbol ANXA1
Gene Full Name annexin A1
Background This gene encodes a membrane-localized protein that binds phospholipids. This protein inhibits phospholipase A2 and has anti-inflammatory activity. Loss of function or expression of this gene has been detected in multiple tumors. [provided by RefSeq, Dec 2014]
Function Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. This protein regulates phospholipase A2 activity. It seems to bind from two to four calcium ions with high affinity. [UniProt]
Cellular Localization Nucleus. Cytoplasm. Cell projection, cilium. Basolateral cell membrane. Note=Found in the cilium, nucleus and basolateral cell membrane of ciliated cells in the tracheal endothelium. Found in the cytoplasm of type II pneumocytes and alveolar macrophages.
Research Area Signaling Transduction antibody
Calculated MW 39 kDa
PTM Phosphorylated by protein kinase C, EGFR and TRPM7 (PubMed:2457390, PubMed:15485879). Phosphorylated in response to EGF treatment (PubMed:2532504).
Sumoylated.