ARG43663

anti-Anoctamin 5 antibody

anti-Anoctamin 5 antibody for Western blot and Human,Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes Anoctamin 5
Tested Reactivity Hu, Ms, Rat
Tested Application WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name Anoctamin 5
Antigen Species Human
Immunogen Recombinant fragment corresponding to a.a. 1-300 of Human Anoctamin 5.
Conjugation Un-conjugated
Protein Full Name Anoctamin-5
Alternate Names TMEM16E; Transmembrane protein 16E; GDD1; LGMD2L; Anoctamin-5; Gnathodiaphyseal dysplasia 1 protein; Limb Girdle Muscular Dystrophy 2L (Autosomal Recessive); Integral Membrane Protein GDD1; LGMDR12

Application Instructions

Predict Reactivity Note Human
Application Suggestion
Tested Application Dilution
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control Skeletal muscle.

Properties

Form Liquid
Purification Affinity purified.
Buffer PBS, 0.01% Thiomersal and 50% Glycerol.
Preservative 0.01% Thiomersal
Stabilizer 50% Glycerol
Concentration Batch dependent
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 203859 Human ANO5

GeneID: 233246 Mouse ANO5

Swiss-port # Q75UR0 Mouse Anoctamin-5

Swiss-port # Q75V66 Human Anoctamin-5

Gene Symbol ANO5
Gene Full Name Anoctamin 5
Background This gene encodes a member of the anoctamin family of transmembrane proteins. The encoded protein is likely a calcium activated chloride channel. Mutations in this gene have been associated with gnathodiaphyseal dysplasia. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2009]
Function Does not exhibit calcium-activated chloride channel (CaCC) activity. [UniProt]
Cellular Localization Cell membrane; Endoplasmic reticulum; Membrane [UniProt]
Calculated MW 107 kDa
PTM Glycoprotein [UniProt]