ARG43927
anti-B56 beta antibody
anti-B56 beta antibody for ELISA,Flow cytometry,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes B56 beta |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA, FACS, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | B56 beta |
| Antigen Species | Human |
| Immunogen | Human B56 beta recombinant protein |
| Expression System | E.coli |
| Conjugation | Un-conjugated |
| Protein Full Name | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform |
| Alternate Names | PPP2R5B; Protein Phosphatase 2 Regulatory Subunit B'Beta; B56beta; PR61B; B56B; Serine/Threonine-Protein Phosphatase 2A 56 KDa Regulatory Subunit Beta Isoform; FLJ35411; Serine/Threonine Protein Phosphatase 2A, 56 KDa Regulatory Subunit, Beta Isoform; Protein Phosphatase 2, Regulatory Subunit B (B56), Beta Isoform; Protein Phosphatase 2 Regulatory Subunit B', Beta; PP2A, B Subunit, PR61 Beta Isoform; PP2A, B Subunit, B56 Beta Isoform; PP2A, B Subunit, B' Beta Isoform; PP2A, B Subunit, R5 Beta Isoform; PP2A B Subunit Isoform PR61-Beta; PP2A B Subunit Isoform B56-Beta; PP2A B Subunit Isoform B'-Beta; PP2A B Subunit Isoform R5-Beta |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified with Immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q15173 Human Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta iso |
|---|---|
| Gene Symbol | PPP2R5B |
| Gene Full Name | Protein Phosphatase 2 Regulatory Subunit B'Beta |
| Background | The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a beta isoform of the regulatory subunit B56 subfamily. |
| Function | As the regulatory component of the serine/threonine-protein phosphatase 2A (PP2A) holoenzyme, modulates substrate specificity, subcellular localization, and responsiveness to phosphorylation. The phosphorylated form mediates the interaction between PP2A and AKT1, leading to AKT1 dephosphorylation. |
| Cellular Localization | Cytoplasm |
| Calculated MW | 57 kDa |
| PTM | Phosphoprotein, Ubl conjugation |
