ARG66685

anti-BACH1 phospho (Ser445) antibody

anti-BACH1 phospho (Ser445) antibody for Western blot and Human

Overview

Product Description Rabbit Polyclonal antibody recognizes BACH1 phospho (Ser445)
Tested Reactivity Hu
Predict Reactivity Ms
Tested Application WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name BACH1
Antigen Species Human
Immunogen Phosphospecific peptide around Ser445 of Human BACH1.
Conjugation Un-conjugated
Alternate Names Transcription regulator protein BACH1; BTBD24; BTB and CNC homolog 1; BACH-1; HA2303

Application Instructions

Application Suggestion
Tested Application Dilution
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control HeLa
Observed Size ~ 105 kDa

Properties

Form Liquid
Purification Affinity purification with phospho-specific peptide and the non-phospho specific antibodies were removed by chromatography using non-phosphopeptide.
Buffer PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Concentration 1 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 571 Human BACH1

Swiss-port # O14867 Human Transcription regulator protein BACH1

Gene Symbol BACH1
Gene Full Name BTB and CNC homology 1, basic leucine zipper transcription factor 1
Background This gene encodes a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family (CNC-bZip). The encoded protein contains broad complex, tramtrack, bric-a-brac/poxvirus and zinc finger (BTB/POZ) domains, which is atypical of CNC-bZip family members. These BTB/POZ domains facilitate protein-protein interactions and formation of homo- and/or hetero-oligomers. When this encoded protein forms a heterodimer with MafK, it functions as a repressor of Maf recognition element (MARE) and transcription is repressed. Multiple alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, May 2009]
Function Transcriptional regulator that acts as repressor or activator. Binds, in vitro, to NF-E2 binding sites. Play important roles in coordinating transcription activation and repression by MAFK. [UniProt]
Cellular Localization Nucleus. [UniProt]
Calculated MW 82 kDa