ARG23500
anti-BAP / Bone Alkaline Phosphatase antibody [BGN/03/662]
anti-BAP / Bone Alkaline Phosphatase antibody [BGN/03/662] for ELISA,Western blot and Bacteria,Human
Overview
| Product Description | Mouse Monoclonal antibody [BGN/03/662] recognizes BAP / Bone Alkaline Phosphatase. Mouse anti Human Alkaline Phosphatase antibody, clone BGN/03/662 recognizes bone specific alkaline phosphatase, a tetrameric glycoprotein found on the surface of oseoblast cells. It is normally present in high concentrations in growing bone and in bile and is released into the blood during injury and bone growth. Elevated levels can infer several conditions including Paget's disease and osteocarcinoma. |
|---|---|
| Tested Reactivity | Hu, Bacteria |
| Tested Application | ELISA, WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | BGN/03/662 |
| Isotype | IgG1 |
| Target Name | BAP / Bone Alkaline Phosphatase |
| Antigen Species | Human |
| Immunogen | Alkaline phosphatase from Human bone. |
| Conjugation | Un-conjugated |
| Alternate Names | PALP; PLAP; EC 3.1.3.1; Alkaline phosphatase Regan isozyme; Placental alkaline phosphatase 1; PLAP-1; Alkaline phosphatase, placental type; ALP |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A. |
| Buffer | PBS and 0.09% Sodium azide. |
| Preservative | 0.09% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P05187 Human Alkaline phosphatase, placental type |
|---|---|
| Gene Symbol | ALPP |
| Gene Full Name | alkaline phosphatase, placental |
| Background | The protein encoded by this gene is an alkaline phosphatase, a metalloenzyme that catalyzes the hydrolysis of phosphoric acid monoesters. It belongs to a multigene family composed of four alkaline phosphatase isoenzymes. The enzyme functions as a homodimer and has a catalytic site containing one magnesium and two zinc ions, which are required for its enzymatic function. The protein is primarily expressed in placental and endometrial tissue; however, strong ectopic expression has been detected in ovarian adenocarcinoma, serous cystadenocarcinoma, and other ovarian cancer cells. [provided by RefSeq, Jan 2015] |
| Calculated MW | 58 kDa |
