ARG57047
anti-BCAT1 antibody [3C8]
anti-BCAT1 antibody [3C8] for Western blot and Human
Overview
| Product Description | Mouse Monoclonal antibody [3C8] recognizes BCAT1 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 3C8 |
| Isotype | IgG1, kappa |
| Target Name | BCAT1 |
| Antigen Species | Human |
| Immunogen | Recombinant fragment around aa. 1-386 of Human BCAT1. |
| Conjugation | Un-conjugated |
| Alternate Names | EC 2.6.1.42; c; BCT1; ECA39; PP18; Branched-chain-amino-acid aminotransferase, cytosolic; PNAS121; MECA39; Protein ECA39; BCAT; BCATC |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A. |
| Buffer | PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 10% Glycerol |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P54687 Human Branched-chain-amino-acid aminotransferase, cytosolic |
|---|---|
| Gene Symbol | BCAT1 |
| Gene Full Name | branched chain amino-acid transaminase 1, cytosolic |
| Background | This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia. As there is also a gene encoding a mitochondrial form of this enzyme, mutations in either gene may contribute to these disorders. Alternatively spliced transcript variants have been described. [provided by RefSeq, May 2010] |
| Function | Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine. [UniProt] |
| Calculated MW | 43 kDa |
