ARG43661
anti-BCLAF1 / BTF antibody
anti-BCLAF1 / BTF antibody for Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes BCLAF1 / BTF |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | BCLAF1 / BTF |
| Antigen Species | Human |
| Immunogen | Synthetic peptide within a.a. 550 to C-terminal of Human BCLAF1 / BTF. |
| Conjugation | Un-conjugated |
| Protein Full Name | Bcl-2-associated transcription factor 1 |
| Alternate Names | Bcl-2-associated transcription factor 1; Btf; BTF; bK211L9.1 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Observed Size | ~150 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS, 0.01% Thiomersal and 50% Glycerol. |
| Preservative | 0.01% Thiomersal |
| Stabilizer | 50% Glycerol |
| Concentration | Batch dependent |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q8K019 Mouse Bcl-2-associated transcription factor 1 Swiss-port # Q9NYF8 Human Bcl-2-associated transcription factor 1 |
|---|---|
| Gene Symbol | BCLAF1 |
| Gene Full Name | BCL2-associated transcription factor 1 |
| Background | This gene encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. The protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope in cells undergoing apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Function | Death-promoting transcriptional repressor. May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA. [UniProt] |
| Calculated MW | 106 kDa |
| PTM | Citrullinated by PADI4. [UniProt] |
