ARG44016
anti-BCMA antibody
anti-BCMA antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes BCMA |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | BCMA |
| Antigen Species | Human |
| Immunogen | Human BCMA recombinantprotein |
| Conjugation | Un-conjugated |
| Protein Full Name | Tumor necrosis factor receptor superfamily member 17 |
| Alternate Names | TNFRSF17; TNF Receptor Superfamily Member 17; BCM; TNFRSF13A; CD269; BCMA; Tumor Necrosis Factor Receptor Superfamily Member 17; B-Cell Maturation Protein; Tumor Necrosis Factor Receptor Superfamily, Member 17; B Cell Maturation Antigen; B-Cell Maturation Factor; CD269 Antigen |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS containing 0.02% sodium azide |
| Preservative | 0.02% sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q02223 Human Tumor necrosis factor receptor superfamily member 17 |
|---|---|
| Gene Symbol | TNFRSF17 |
| Gene Full Name | TNF Receptor Superfamily Member 17 |
| Background | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. |
| Function | Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK |
| Cellular Localization | Cell membrane, Membrane |
| Calculated MW | 20 kDa |
| PTM | Disulfide bond |
