ARG66939

anti-BCMA antibody [SQab22269]

anti-BCMA antibody [SQab22269] for IHC-Formalin-fixed paraffin-embedded sections and Human

Cancer antibody; Immune System antibody; Signaling Transduction antibody

Overview

Product Description Recombinant Rabbit Monoclonal antibody [SQab22269] recognizes BCMA
Tested Reactivity Hu
Tested Application IHC-P
Host Rabbit
Clonality Monoclonal
Clone SQab22269
Isotype IgG
Target Name BCMA
Antigen Species Human
Immunogen Full length protein corresponding to Human BCMA.
Conjugation Un-conjugated
Protein Full Name Tumor necrosis factor receptor superfamily member 17
Alternate Names BCM; BCMA; CD269; CD antigen CD269; Tumor necrosis factor receptor superfamily member 17; B-cell maturation protein; TNFRSF13A

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P1:100 - 1:200
Application Note IHC-P: Antigen Retrieval: Heat mediated was performed using Tris/EDTA buffer (pH 9.0). Incubate the samples at RT (18-25°C) for 48 min.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control Human DBLCL

Properties

Form Liquid
Purification Purification with Protein A.
Buffer PBS, 0.01% Sodium azide, 40% Glycerol and 0.05%BSA.
Preservative 0.01% Sodium azide
Stabilizer 40% Glycerol and 0.05%BSA
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 608 Human TNFRSF17

Swiss-port # Q02223 Human Tumor necrosis factor receptor superfamily member 17

Gene Symbol TNFRSF17
Gene Full Name tumor necrosis factor receptor superfamily, member 17
Background The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. [provided by RefSeq, Jul 2008]
Function Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK. [UniProt]
Research Area Cancer antibody; Immune System antibody; Signaling Transduction antibody
Calculated MW 20 kDa