ARG66939
anti-BCMA antibody [SQab22269]
anti-BCMA antibody [SQab22269] for IHC-Formalin-fixed paraffin-embedded sections and Human
Cancer antibody; Immune System antibody; Signaling Transduction antibody
Overview
| Product Description | Recombinant Rabbit Monoclonal antibody [SQab22269] recognizes BCMA |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone | SQab22269 |
| Isotype | IgG |
| Target Name | BCMA |
| Antigen Species | Human |
| Immunogen | Full length protein corresponding to Human BCMA. |
| Conjugation | Un-conjugated |
| Protein Full Name | Tumor necrosis factor receptor superfamily member 17 |
| Alternate Names | BCM; BCMA; CD269; CD antigen CD269; Tumor necrosis factor receptor superfamily member 17; B-cell maturation protein; TNFRSF13A |
Application Instructions
| Application Suggestion |
|
||||
|---|---|---|---|---|---|
| Application Note | IHC-P: Antigen Retrieval: Heat mediated was performed using Tris/EDTA buffer (pH 9.0). Incubate the samples at RT (18-25°C) for 48 min. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
||||
| Positive Control | Human DBLCL |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A. |
| Buffer | PBS, 0.01% Sodium azide, 40% Glycerol and 0.05%BSA. |
| Preservative | 0.01% Sodium azide |
| Stabilizer | 40% Glycerol and 0.05%BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q02223 Human Tumor necrosis factor receptor superfamily member 17 |
|---|---|
| Gene Symbol | TNFRSF17 |
| Gene Full Name | tumor necrosis factor receptor superfamily, member 17 |
| Background | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. [provided by RefSeq, Jul 2008] |
| Function | Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK. [UniProt] |
| Research Area | Cancer antibody; Immune System antibody; Signaling Transduction antibody |
| Calculated MW | 20 kDa |
