ARG56816
anti-BD1 / beta Defensin 1 antibody (Biotin)
anti-BD1 / beta Defensin 1 antibody (Biotin) for ELISA,Western blot and Human
Overview
Product Description | Biotin-conjugated Rabbit Polyclonal antibody recognizes BD1 / beta Defensin 1 |
---|---|
Tested Reactivity | Hu |
Tested Application | ELISA, WB |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | BD1 / beta Defensin 1 |
Antigen Species | Human |
Immunogen | E.coli derived Recombinant Human BD-1 (47 aa). (GNFLTGLGHR SDHYNCVSSG GQCLYSACPI FTKIQGTCYR GKAKCCK) |
Conjugation | Biotin |
Alternate Names | DEFB-1; Defensin, beta 1; HBD1; hBD-1; BD1; Beta-defensin 1; DEFB101; BD-1 |
Application Instructions
Application Suggestion |
|
||||||
---|---|---|---|---|---|---|---|
Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
Form | Liquid |
---|---|
Purification | Purified by affinity chromatography. |
Buffer | PBS (pH 7.2) |
Concentration | 1 mg/ml |
Storage Instruction | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links | |
---|---|
Gene Symbol | DEFB1 |
Gene Full Name | defensin, beta 1 |
Background | Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. Beta Defensin 1 is an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis. [provided by RefSeq, Jul 2008] |
Function | Beta Defensin 1 has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility (PubMed:25122636). [UniProt] |
Calculated MW | 7 kDa |