ARG63165
anti-BIF1 / SH3GLB1 antibody
anti-BIF1 / SH3GLB1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Cell Biology and Cellular Response antibody; Cell Death antibody; Metabolism antibody
Overview
Product Description | Goat Polyclonal antibody recognizes BIF1 / SH3GLB1 |
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Tested Reactivity | Hu |
Predict Reactivity | Ms, Rat, Cow, Dog |
Tested Application | IHC-P, WB |
Host | Goat |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | BIF1 / SH3GLB1 |
Antigen Species | Human |
Immunogen | C-QKGKVPITYLELLN |
Conjugation | Un-conjugated |
Alternate Names | SH3 domain-containing GRB2-like protein B1; Bif-1; Endophilin-B1; dJ612B15.2; Bax-interacting factor 1; CGI-61; PPP1R70 |
Application Instructions
Application Suggestion |
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Application Note | WB: Recommend incubate at RT for 1h. IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
Form | Liquid |
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Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
Preservative | 0.02% Sodium azide |
Stabilizer | 0.5% BSA |
Concentration | 0.5 mg/ml |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links | |
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Background | This gene encodes a SRC homology 3 domain-containing protein. The encoded protein interacts with the proapoptotic member of the Bcl-2 family, Bcl-2-associated X protein (Bax) and may be involved in regulating apoptotic signaling pathways. This protein may also be involved in maintaining mitochondrial morphology. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011] |
Research Area | Cell Biology and Cellular Response antibody; Cell Death antibody; Metabolism antibody |
Calculated MW | 41 kDa |
PTM | Phosphorylated at Thr-145 by CDK5; this phosphorylation is required for autophagy induction in starved neurons and facilitates homodimerization. |