ARG54459
anti-BRD2 antibody
anti-BRD2 antibody for Western blot and Human
Cell Biology and Cellular Response antibody; Gene Regulation antibody; Signaling Transduction antibody
Overview
Product Description | Goat Polyclonal antibody recognizes BRD2 |
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Tested Reactivity | Hu |
Tested Application | WB |
Specificity | This antibody reacts with human BRD2. The specific epitope is in the region between aa 550 and 600 of human BRD2. Based on 100% sequence identity, this antibody is predicted to react with Bovine, Rhesus Monkey, Gorilla, White-tufted-ear marmoset, Crab-eating macaque and Northern white-cheeked gibbon. |
Host | Goat |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | BRD2 |
Antigen Species | Human |
Immunogen | Synthetic peptide representing a portion of the protein between the putative nuclear localization signal and the ET domain |
Conjugation | Un-conjugated |
Alternate Names | O27.1.1; FSH; RING3; D6S113E; FSRG1; Really interesting new gene 3 protein; NAT; Bromodomain-containing protein 2; RNF3 |
Application Instructions
Predict Reactivity Note | Bovine, Rhesus Monkey, Gorilla, White-tufted-ear marmoset, Crab-eating macaque and Northern white-cheeked gibbon. | ||||
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Application Suggestion |
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Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
Positive Control | HeLa |
Properties
Form | Liquid |
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Purification | Affinity-purified with an epitope specific to BRD2 immobilized on solid support. |
Buffer | Tris-citrate/phosphate (pH 7-8) and 0.09% Sodium azide |
Preservative | 0.09% Sodium azide |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links | |
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Gene Symbol | BRD2 |
Gene Full Name | bromodomain containing 2 |
Background | BRD2 (bromodomain-containing 2) is a nuclear mitogen-activated kinase that plays a role in transcription of cell-cycle-regulated genes by functioning as an adapter protein that recruits E2F and chromatin remodeling factors to E2F response elements. |
Function | May play a role in spermatogenesis or folliculogenesis (By similarity). Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling. Regulates transcription of the CCND1 gene. Plays a role in nucleosome assembly. [UniProt] |
Research Area | Cell Biology and Cellular Response antibody; Gene Regulation antibody; Signaling Transduction antibody |
Calculated MW | 88 kDa |