ARG55853
anti-C1GALT1 antibody
anti-C1GALT1 antibody for Western blot and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes C1GALT1 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | C1GALT1 |
| Antigen Species | Human |
| Immunogen | KLH-conjugated synthetic peptide corresponding to aa. 115-144 (Center) of Human C1GALT1. |
| Conjugation | Un-conjugated |
| Alternate Names | T-synthase; C1GALT; Core 1 beta3-Gal-T1; C1GalT1; B3Gal-T8; Core 1 beta1,3-galactosyltransferase 1; Beta-1,3-galactosyltransferase; Core 1 O-glycan T-synthase; EC 2.4.1.122; Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1; Core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | Mouse kidney |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A and immunogen peptide. |
| Buffer | PBS and 0.09% (W/V) Sodium azide |
| Preservative | 0.09% (W/V) Sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q9JJ06 Mouse Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 Swiss-port # Q9NS00 Human Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 |
|---|---|
| Gene Symbol | C1GALT1 |
| Gene Full Name | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 |
| Background | The protein encoded by this gene generates the common core 1 O-glycan structure, Gal-beta-1-3GalNAc-R, by the transfer of Gal from UDP-Gal to GalNAc-alpha-1-R. Core 1 is a precursor for many extended mucin-type O-glycans on cell surface and secreted glycoproteins. Studies in mice suggest that this gene plays a key role in thrombopoiesis and kidney homeostasis.[provided by RefSeq, Sep 2010] |
| Function | Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Plays a central role in many processes, such as angiogenesis, thrombopoiesis and kidney homeostasis development. [UniProt] |
| Cellular Localization | Membrane; Single-pass type II membrane protein |
| Calculated MW | 42 kDa |
