ARG63094
anti-CA19-9 antibody [121SLE]
anti-CA19-9 antibody [121SLE] for ELISA,IHC-Formalin-fixed paraffin-embedded sections and Human
Cancer antibody; Cell Biology and Cellular Response antibody; Controls and Markers antibody
Overview
| Product Description | Mouse Monoclonal antibody [121SLE] recognizes CA19-9 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA, IHC-P |
| Specificity | The clone 121SLE recognizes Sialyl Lewis a containing glycolipids (CA19-9). |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 121SLE |
| Isotype | IgM |
| Target Name | CA19-9 |
| Immunogen | Immunoprecipitate obtained after immunodiffusion of MAb 19-9 and mucins isolated from an ovarian cyst of a 0Le(a+b-) patient. |
| Conjugation | Un-conjugated |
| Alternate Names | SIAT7F; SIAT7-F; ST6GALNACV; CA19-9 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|---|---|
| Application Note | IHC-P: Positive control:colorectal adenocarcinoma Application note:heat mediated antigen retrieval (sodium citrate); mAb incubation 1 hour / RT; detection DAB * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from ascites by precipitation methods and size-exclusion chromatography. |
| Purity | > 95% (by SDS-PAGE) |
| Buffer | TBS (pH 8.0) and 15 mM Sodium azide |
| Preservative | 15 mM Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
GeneID: 30815 Human ST6GALNAC6 Swiss-port # Q969X2 Human Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 |
|---|---|
| Gene Symbol | ST6GALNAC6 |
| Gene Full Name | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 |
| Background | ST6GALNAC6 belongs to a family of sialyltransferases that modify proteins and ceramides on the cell surface to alter cell-cell or cell-extracellular matrix interactions (Tsuchida et al., 2003 [PubMed 12668675]).[supplied by OMIM, Mar 2008] |
| Function | Alpha-2,6-sialyltransferase involved in the synthesis of alpha-series gangliosides. Has activity toward GD1a, GT1b and GM1b. Has no activity toward glycoproteins. Responsible for the biosynthesis of DSGG (disialylgalactosylgloboside) from MSGG (monosialylgalactosylgloboside) in normal and malignant kidney. Participates in the synthesis of disialyl Lewis a (Le(a)). [UniProt] |
| Highlight | Related products: CA19-9 antibodies; CA19-9 ELISA Kits; Anti-Mouse IgM secondary antibodies; Related news: More than a biomarker, CA19-9 is a therapeutic target of pancreatic cancer |
| Research Area | Cancer antibody; Cell Biology and Cellular Response antibody; Controls and Markers antibody |
| Calculated MW | 38 kDa |
