ARG23513

anti-CA2 / Carbonic Anhydrase 2 antibody

anti-CA2 / Carbonic Anhydrase 2 antibody for Immunodiffusion,ICC/IF,Western blot and Human

Overview

Product Description Sheep Polyclonal antibody recognizes CA2 / Carbonic Anhydrase 2
Tested Reactivity Hu
Tested Application ICC/IF, ID, WB
Host Sheep
Clonality Polyclonal
Isotype IgG
Target Name CA2 / Carbonic Anhydrase 2
Antigen Species Human
Immunogen Purified Human carbonic anhydrase II (CA2) prepared from erythrocytes.
Conjugation Un-conjugated
Alternate Names Carbonic anhydrase C; EC 4.2.1.1; Car2; Carbonate dehydratase II; CA-II; Carbonic anhydrase II; CAC; HEL-76; Carbonic anhydrase 2; CAII

Application Instructions

Application Suggestion
Tested Application Dilution
ICC/IFAssay-dependent
IDAssay-dependent
WB1:1000
Application Note WB: This product recognizes a band of ~18 kDa in Rat adrenomedullary chromaffin cell lysates.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified by ion exchange chromatography.
Buffer Glycine buffered saline, 0.09% Sodium azide, 0.01% Benzamidine, 0.1% EACA and 1m MEDTA.
Preservative 0.09% Sodium azide and 0.01% Benzamidine
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 760 Human CA2

Swiss-port # P00918 Human Carbonic anhydrase 2

Gene Symbol CA2
Gene Full Name carbonic anhydrase II
Background The protein encoded by this gene is one of several isozymes of carbonic anhydrase, which catalyzes reversible hydration of carbon dioxide. Defects in this enzyme are associated with osteopetrosis and renal tubular acidosis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014]
Function Essential for bone resorption and osteoclast differentiation (By similarity). Reversible hydration of carbon dioxide. Can hydrate cyanamide to urea. Involved in the regulation of fluid secretion into the anterior chamber of the eye. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6. [UniProt]
Calculated MW 29 kDa