ARG58363
anti-CA5A / Carbonic Anhydrase 5A antibody
anti-CA5A / Carbonic Anhydrase 5A antibody for Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes CA5A / Carbonic Anhydrase 5A |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | CA5A / Carbonic Anhydrase 5A |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 39-305 of Human CA5A (NP_001730.1). |
| Conjugation | Un-conjugated |
| Alternate Names | EC 4.2.1.1; Carbonic anhydrase VA; Carbonic anhydrase 5A, mitochondrial; GS1-21A4.1; CA5; CAV; CA5AD; Carbonate dehydratase VA; CAVA; CA-VA |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | LO2 | ||||
| Observed Size | 35 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P35218 Human Carbonic anhydrase 5A, mitochondrial |
|---|---|
| Gene Symbol | CA5A |
| Gene Full Name | carbonic anhydrase VA, mitochondrial |
| Background | Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA VA is localized in the mitochondria and expressed primarily in the liver. It may play an important role in ureagenesis and gluconeogenesis. CA5A gene maps to chromosome 16q24.3 and an unprocessed pseudogene has been assigned to 16p12-p11.2. [provided by RefSeq, Jul 2008] |
| Function | Reversible hydration of carbon dioxide. Low activity. [UniProt] |
| Cellular Localization | Mitochondrion,. [UniProt] |
| Calculated MW | 35 kDa |
