ARG57035
anti-CACYBP antibody [3G8]
anti-CACYBP antibody [3G8] for Western blot and Human
Overview
| Product Description | Mouse Monoclonal antibody [3G8] recognizes CACYBP |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 3G8 |
| Isotype | IgG2a, kappa |
| Target Name | CACYBP |
| Antigen Species | Human |
| Immunogen | Recombinant fragment around aa. 1-185 of Human CACYBP. |
| Conjugation | Un-conjugated |
| Alternate Names | S100A6-binding protein; SIP; S100A6BP; GIG5; hCacyBP; CacyBP; Siah-interacting protein; Calcyclin-binding protein; PNAS-107 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A. |
| Buffer | PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 10% Glycerol |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | CACYBP |
| Gene Full Name | calcyclin binding protein |
| Background | The protein encoded by this gene is a calcyclin binding protein. It may be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. It probably serves as a molecular bridge in ubiquitin E3 complexes and participates in the ubiquitin-mediated degradation of beta-catenin. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Function | May be involved in calcium-dependent ubiquitination and subsequent proteasomal degradation of target proteins. Probably serves as a molecular bridge in ubiquitin E3 complexes. Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1). [UniProt] |
| Calculated MW | 26 kDa |
| PTM | Phosphorylated on serine residues. Phosphorylated upon induction by RA or at high calcium concentrations. |
