ARG44893
anti-CAST antibody
anti-CAST antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
Overview
| Product Description | Mouse Monoclonal antibody recognizes CAST |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Target Name | CAST |
| Antigen Species | Human |
| Conjugation | Un-conjugated |
| Alternate Names | POLR1G; RNA Polymerase I Subunit G; ASE-1; PAF49; CAST; CD3EAP; RPA34; A34.5; CD3e Antigen, Epsilon Polypeptide Associated Protein; DNA-Directed RNA Polymerase I Subunit RPA34; RNA Polymerase I-Associated Factor PAF49; DNA-Directed RNA Polymerase I Subunit G; CD3e Molecule Associated Protein; Antisense To ERCC-1 Protein; ASE1; CD3e Molecule, Epsilon Associated Protein; CD3 Epsilon Associated Protein; CD3-Epsilon-Associated Protein; CD3E-Associated Protein; Antisense To ERCC 1 |
Application Instructions
| Application Suggestion |
|
||||
|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Protein A purification |
| Buffer | PBS with 0.09% sodium azide |
| Preservative | 0.09% sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | POLR1G |
|---|---|
| Gene Full Name | RNA Polymerase I Subunit G |
| Background | Enables RNA binding activity. Predicted to be involved in transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to act upstream of or within rRNA transcription. Located in cytosol; mitochondrion; and nuclear lumen. [provided by Alliance of Genome Resources, Apr 2022] |
| Function | Component of RNA polymerase I (Pol I), a DNA-dependent RNA polymerase which synthesizes ribosomal RNA precursors using the four ribonucleoside triphosphates as substrates. Involved in UBTF-activated transcription, presumably at a step following PIC formation |
| Cellular Localization | Chromosome, DNA-directed RNA polymerase, Nucleus |
| Calculated MW | 55 kDa |
| PTM | Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugation |
