ARG58279

anti-CBG / SerpinA6 antibody

anti-CBG / SerpinA6 antibody for Western blot and Human

Overview

Product Description Rabbit Polyclonal antibody recognizes CBG / SerpinA6
Tested Reactivity Hu
Tested Application WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name CBG / SerpinA6
Antigen Species Human
Immunogen KLH-conjugated synthetic peptide corresponding to aa. 197-225 (Center) of Human CBG / SerpinA6.
Conjugation Un-conjugated
Alternate Names Serpin A6; Corticosteroid-binding globulin; CBG; Transcortin

Application Instructions

Application Suggestion
Tested Application Dilution
WB1:1000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control Human blood plasma

Properties

Form Liquid
Purification Purification with Protein A and immunogen peptide.
Buffer PBS and 0.09% (W/V) Sodium azide.
Preservative 0.09% (W/V) Sodium azide.
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 866 Human SERPINA6

Swiss-port # P08185 Human Corticosteroid-binding globulin

Gene Symbol SERPINA6
Gene Full Name serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
Background This gene encodes an alpha-globulin protein with corticosteroid-binding properties. This is the major transport protein for glucorticoids and progestins in the blood of most vertebrates. The gene localizes to a chromosomal region containing several closely related serine protease inhibitors which may have evolved by duplication events. [provided by RefSeq, Jul 2008]
Function Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species. [UniProt]
Cellular Localization Secreted. [UniProt]
Calculated MW 45 kDa
PTM N-glycosylated; binds 5 oligosaccharide chains.

Glycosylation in position Asn-260 is needed for steroid binding. [UniProt]