ARG59137
anti-CCL19 / MIP-3 beta antibody
anti-CCL19 / MIP-3 beta antibody for Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes CCL19 / MIP-3 beta |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | CCL19 / MIP-3 beta |
| Antigen Species | Human |
| Immunogen | Synthetic peptide derived from Human CCL19 / MIP-3 beta. |
| Conjugation | Un-conjugated |
| Alternate Names | Small-inducible cytokine A19; EBI1 ligand chemokine; CKb11; SCYA19; ELC; MIP-3b; MIP3B; C-C motif chemokine 19; Macrophage inflammatory protein 3 beta; Epstein-Barr virus-induced molecule 1 ligand chemokine; Beta-chemokine exodus-3; CK beta-11; MIP-3-beta |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Observed Size | ~ 11 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.4), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | CCL19 |
| Gene Full Name | chemokine (C-C motif) ligand 19 |
| Background | This antimicrobial gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene may play a role in normal lymphocyte recirculation and homing. It also plays an important role in trafficking of T cells in thymus, and in T cell and B cell migration to secondary lymphoid organs. It specifically binds to chemokine receptor CCR7. [provided by RefSeq, Sep 2014] |
| Function | May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4. [UniProt] |
| Cellular Localization | Secreted. [UniProt] |
| Calculated MW | 11 kDa |
