ARG56595
anti-CCL22 / MDC antibody [1.3_1C6-1D3]
anti-CCL22 / MDC antibody [1.3_1C6-1D3] for ELISA,Western blot and Human
Overview
| Product Description | Mouse Monoclonal antibody [1.3_1C6-1D3] recognizes CCL22 / MDC |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA, WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 1.3_1C6-1D3 |
| Isotype | IgG1, kappa |
| Target Name | CCL22 / MDC |
| Antigen Species | Human |
| Immunogen | E.coli derived Recombinant Human MDC (CCL22). (YGANMEDSVC CRDYVRYRLP LRVVKHFYWT SDSCPRPGVV LLTFRDKEIC ADPRVPWVKM ILNKLSQ) |
| Conjugation | Un-conjugated |
| Alternate Names | CC chemokine STCP-1; Stimulated T-cell chemotactic protein 1; 3-69; Macrophage-derived chemokine; MDC; DC/B-CK; SCYA22; Small-inducible cytokine A22; ABCD-1; 7-69; 1-69; A-152E5.1; STCP-1; 5-69; C-C motif chemokine 22 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A. |
| Buffer | PBS (pH 7.2) |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | CCL22 |
| Gene Full Name | chemokine (C-C motif) ligand 22 |
| Background | This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for monocytes, dendritic cells, natural killer cells and for chronically activated T lymphocytes. It also displays a mild activity for primary activated T lymphocytes and has no chemoattractant activity for neutrophils, eosinophils and resting T lymphocytes. The product of this gene binds to chemokine receptor CCR4. This chemokine may play a role in the trafficking of activated T lymphocytes to inflammatory sites and other aspects of activated T lymphocyte physiology. [provided by RefSeq, Sep 2014] |
| Function | May play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. Chemotactic for monocytes, dendritic cells and natural killer cells. Mild chemoattractant for primary activated T-lymphocytes and a potent chemoattractant for chronically activated T-lymphocytes but has no chemoattractant activity for neutrophils, eosinophils, and resting T-lymphocytes. Binds to CCR4. Processed forms MDC(3-69), MDC(5-69) and MDC(7-69) seem not be active. [UniProt] |
| Calculated MW | 11 kDa |
| PTM | The N-terminal processed forms MDC(3-69), MDC(5-69) and MDC(7-69) are produced by proteolytic cleavage after secretion from monocyte derived dendrocytes. |
