ARG66093
anti-CCL4 / MIP1 beta antibody (Biotin)
anti-CCL4 / MIP1 beta antibody (Biotin) for ELISA,Western blot and Mouse
Overview
Product Description | Biotin-conjugated Rabbit Polyclonal antibody recognizes CCL4 / MIP1 beta |
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Tested Reactivity | Ms |
Tested Application | ELISA, WB |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | CCL4 / MIP1 beta |
Antigen Species | Mouse |
Immunogen | E. coli derived recombinant Mouse CCL4 / MCP1 beta. (APMGSDPPTS CCFSYTSRQL HRSFVMDYYE TSSLCSKPAV VFLTKRGRQI CANPSEPWVT EYMSDLELN) |
Conjugation | Biotin |
Alternate Names | ACT2; G-26; HC21; LAG1; LAG-1; MIP1B; SCYA2; SCYA4; MIP1B1; AT744.1; MIP-1-beta |
Application Instructions
Application Suggestion |
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Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
Form | Liquid |
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Purification | Purified by affinity chromatography. |
Buffer | PBS (pH 7.2) |
Concentration | 1 mg/ml |
Storage Instruction | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links | |
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Gene Symbol | Ccl4 |
Gene Full Name | chemokine (C-C motif) ligand 4 |
Background | The protein encoded by this gene is a mitogen-inducible monokine and is one of the major HIV-suppressive factors produced by CD8+ T-cells. The encoded protein is secreted and has chemokinetic and inflammatory functions. [provided by RefSeq, Dec 2012] |
Function | Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B. [UniProt] |
Calculated MW | 10 kDa |