ARG64951

anti-CCT3 / TCP1 antibody

anti-CCT3 / TCP1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse

Signaling Transduction antibody

Overview

Product Description Goat Polyclonal antibody recognizes CCT3 / TCP1
Tested Reactivity Hu, Ms
Predict Reactivity Cow, Rat, Dog, Pig
Tested Application IHC-P, WB
Specificity This antibody is expected to recognize all reported isoforms (NP_005989.3; NP_001008883.1; NP_001008800.1).
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name CCT3 / TCP1
Antigen Species Human
Immunogen C-GHKKKGDDQSRQGG
Conjugation Un-conjugated
Alternate Names CCT-gamma; PIG48; TRIC5; TCP-1-gamma; T-complex protein 1 subunit gamma; CCTG; hTRiC5

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P5 µg/ml
WB0.01 - 0.03 µg/ml
Application Note WB: Recommend incubate at RT for 1h.
IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 12462 Mouse CCT3

GeneID: 7203 Human CCT3

Swiss-port # P49368 Human T-complex protein 1 subunit gamma

Swiss-port # P80318 Mouse T-complex protein 1 subunit gamma

Background The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants have been characterized for this gene. In addition, a pseudogene of this gene has been found on chromosome 8. [provided by RefSeq, Aug 2010]
Research Area Signaling Transduction antibody
Calculated MW 61 kDa