ARG58346

anti-CCT6A antibody

anti-CCT6A antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes CCT6A
Tested Reactivity Hu, Ms, Rat
Tested Application IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name CCT6A
Antigen Species Human
Immunogen Recombinant fusion protein corresponding to aa. 80-250 of Human CCT6A (NP_001753.1).
Conjugation Un-conjugated
Alternate Names Cctz; CCT-zeta-1; TTCP20; T-complex protein 1 subunit zeta; TCP20; CCT6; CCT-zeta; TCP-1-zeta; HTR3; MoDP-2; TCPZ; Tcp20; Acute morphine dependence-related protein 2

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P1:50 - 1:100
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control U251
Observed Size 58 kDa

Properties

Form Liquid
Purification Affinity purified.
Buffer PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 12466 Mouse CCT6A

GeneID: 908 Human CCT6A

Swiss-port # P40227 Human T-complex protein 1 subunit zeta

Swiss-port # P80317 Mouse T-complex protein 1 subunit zeta

Gene Symbol CCT6A
Gene Full Name chaperonin containing TCP1, subunit 6A (zeta 1)
Background The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized. In addition, several pseudogenes of this gene have been located. [provided by RefSeq, Jun 2010]
Function Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. [UniProt]
Cellular Localization Cytoplasm. [UniProt]
Calculated MW 58 kDa