ARG22084

anti-CD103 / Integrin alpha E antibody [2E7] (PE)

anti-CD103 / Integrin alpha E antibody [2E7] (PE) for Flow cytometry,IHC-Frozen sections,Cellular activation and Mouse

Overview

Product Description PE-conjugated Hamster Monoclonal antibody [2E7] recognizes CD103 / Integrin alpha E
Tested Reactivity Ms
Tested Application Cell-Act , FACS, IHC-Fr
Specificity Mouse CD103
Host Hamster
Clonality Monoclonal
Clone 2E7
Isotype IgG2
Target Name CD103 / Integrin alpha E
Antigen Species Mouse
Immunogen C57BL/6J Mouse intestinal intraepithelial lymphocytes (IEL)
Conjugation PE
Alternate Names CD103; HUMINAE; Integrin alpha-E; Mucosal lymphocyte 1 antigen; CD antigen CD103; HML-1 antigen; Integrin alpha-IEL

Application Instructions

Application Suggestion
Tested Application Dilution
Cell-Act Assay-dependent
FACS< 0.2 µg/10^6 cells
IHC-FrAssay-dependent
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Buffer PBS, 0.1% Sodium azide and Sucrose.
Preservative 0.1% Sodium azide
Stabilizer Sucrose
Concentration 0.1 mg/ml
Storage Instruction Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 16407 Mouse ITGAE

Swiss-port # Q60677 Mouse Integrin alpha-E

Gene Symbol ITGAE
Gene Full Name integrin alpha E, epithelial-associated
Background Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation. [provided by RefSeq, Jul 2008]
Function Integrin alpha-E/beta-7 is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers. [UniProt]
Calculated MW 130 kDa