ARG42400

anti-CD129 / IL9R antibody [AH9R7] (PE)

anti-CD129 / IL9R antibody [AH9R7] (PE) for Flow cytometry and Human

Overview

Product Description PE-conjugated Mouse Monoclonal antibody [AH9R7] recognizes CD129 / IL9R
Tested Reactivity Hu
Tested Application FACS
Specificity The mouse monoclonal antibody AH9R7 recognizes an extracellular epitope of CD129 / IL-9R alpha, a 57 kDa type I transmembrane glycoprotein expressed at low levels by lymphocytes, blood cell progenitors, eosinophils, mast cells, epithelial cells, muscle cells and neurons.
Host Mouse
Clonality Monoclonal
Clone AH9R7
Isotype IgG2b, kappa
Target Name CD129 / IL9R
Antigen Species Human
Immunogen Human CD129-transfected cell line.
Conjugation PE
Alternate Names IL-9R; CD antigen CD129; CD129; IL-9 receptor; Interleukin-9 receptor

Application Instructions

Application Suggestion
Tested Application Dilution
FACS10 µl / 100 µl of whole blood or 10^6 cells
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified
Buffer PBS and 15 mM Sodium azide.
Preservative 15 mM Sodium azide
Storage Instruction Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 3581 Human IL9R

Swiss-port # Q01113 Human Interleukin-9 receptor

Gene Symbol IL9R
Gene Full Name interleukin 9 receptor
Background The protein encoded by this gene is a cytokine receptor that specifically mediates the biological effects of interleukin 9 (IL9). The functional IL9 receptor complex requires this protein as well as the interleukin 2 receptor, gamma (IL2RG), a common gamma subunit shared by the receptors of many different cytokines. The ligand binding of this receptor leads to the activation of various JAK kinases and STAT proteins, which connect to different biologic responses. This gene is located at the pseudoautosomal regions of X and Y chromosomes. Genetic studies suggested an association of this gene with the development of asthma. Multiple pseudogenes on chromosome 9, 10, 16, and 18 have been described. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]
Function This is a receptor for interleukin-9. [UniProt]
Cellular Localization Cell membrane; Single-pass type I membrane protein. Secreted. [UniProt]
Calculated MW 57 kDa