ARG42392
anti-CD129 / IL9R antibody [AH9R7] (low endotoxin)
anti-CD129 / IL9R antibody [AH9R7] (low endotoxin) for ELISA,Functional study,Flow cytometry and Human
Overview
| Product Description | Azide free and low endotoxin Mouse Monoclonal antibody [AH9R7] recognizes CD129 / IL9R |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA, FACS, FuncSt |
| Specificity | The mouse monoclonal antibody AH9R7 recognizes an extracellular epitope of CD129 / IL-9R alpha, a 57 kDa type I transmembrane glycoprotein expressed at low levels by lymphocytes, blood cell progenitors, eosinophils, mast cells, epithelial cells, muscle cells and neurons. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | AH9R7 |
| Isotype | IgG2b, kappa |
| Target Name | CD129 / IL9R |
| Antigen Species | Human |
| Immunogen | Human CD129-transfected cell line. |
| Conjugation | Un-conjugated |
| Alternate Names | IL-9R; CD antigen CD129; CD129; IL-9 receptor; Interleukin-9 receptor |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A. |
| Purification Note | 0.2 µm filter sterilized. Endotoxin level is less than 0.01 EU/µg of the protein. |
| Buffer | PBS |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | IL9R |
| Gene Full Name | interleukin 9 receptor |
| Background | The protein encoded by this gene is a cytokine receptor that specifically mediates the biological effects of interleukin 9 (IL9). The functional IL9 receptor complex requires this protein as well as the interleukin 2 receptor, gamma (IL2RG), a common gamma subunit shared by the receptors of many different cytokines. The ligand binding of this receptor leads to the activation of various JAK kinases and STAT proteins, which connect to different biologic responses. This gene is located at the pseudoautosomal regions of X and Y chromosomes. Genetic studies suggested an association of this gene with the development of asthma. Multiple pseudogenes on chromosome 9, 10, 16, and 18 have been described. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008] |
| Function | This is a receptor for interleukin-9. [UniProt] |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein. Secreted. [UniProt] |
| Calculated MW | 57 kDa |
