ARG42420
anti-CD132 / IL2RG antibody [TUGh4] (PE)
anti-CD132 / IL2RG antibody [TUGh4] (PE) for Flow cytometry and Human,Dog
Overview
| Product Description | PE-conjugated Rat Monoclonal antibody [TUGh4] recognizes CD132 / IL2RG |
|---|---|
| Tested Reactivity | Hu, Dog |
| Tested Application | FACS |
| Specificity | The rat monoclonal antibody TUGh4 recognizes an extracellular epitope of CD132 (the common gamma chain), a 65-70 kDa type I transmembrane glycoprotein broadly expressed by most leukocytes. |
| Host | Rat |
| Clonality | Monoclonal |
| Clone | TUGh4 |
| Isotype | IgG2b, kappa |
| Target Name | CD132 / IL2RG |
| Antigen Species | Human |
| Immunogen | Human CD132-transfected cell line. |
| Conjugation | PE |
| Alternate Names | IL-2R subunit gamma; IMD4; CD132; P64; p64; CD antigen CD132; Interleukin-2 receptor subunit gamma; SCIDX; CIDX; Cytokine receptor common subunit gamma; gammaC; SCIDX1; IL-2 receptor subunit gamma; IL-2RG |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified |
| Buffer | PBS and 15 mM Sodium azide. |
| Preservative | 15 mM Sodium azide |
| Storage Instruction | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P31785 Human Cytokine receptor common subunit gamma |
|---|---|
| Gene Symbol | IL2RG |
| Gene Full Name | interleukin 2 receptor, gamma |
| Background | The protein encoded by this gene is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder. [provided by RefSeq, Mar 2010] |
| Function | Common subunit for the receptors for a variety of interleukins. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15 (PubMed:15123770). [UniProt] |
| Cellular Localization | Membrane; Single-pass type I membrane protein. [UniProt] |
| Calculated MW | 42 kDa |
