ARG42420

anti-CD132 / IL2RG antibody [TUGh4] (PE)

anti-CD132 / IL2RG antibody [TUGh4] (PE) for Flow cytometry and Human,Dog

Overview

Product Description PE-conjugated Rat Monoclonal antibody [TUGh4] recognizes CD132 / IL2RG
Tested Reactivity Hu, Dog
Tested Application FACS
Specificity The rat monoclonal antibody TUGh4 recognizes an extracellular epitope of CD132 (the common gamma chain), a 65-70 kDa type I transmembrane glycoprotein broadly expressed by most leukocytes.
Host Rat
Clonality Monoclonal
Clone TUGh4
Isotype IgG2b, kappa
Target Name CD132 / IL2RG
Antigen Species Human
Immunogen Human CD132-transfected cell line.
Conjugation PE
Alternate Names IL-2R subunit gamma; IMD4; CD132; P64; p64; CD antigen CD132; Interleukin-2 receptor subunit gamma; SCIDX; CIDX; Cytokine receptor common subunit gamma; gammaC; SCIDX1; IL-2 receptor subunit gamma; IL-2RG

Application Instructions

Application Suggestion
Tested Application Dilution
FACS10 µl / 100 µl of whole blood or 10^6 cells
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified
Buffer PBS and 15 mM Sodium azide.
Preservative 15 mM Sodium azide
Storage Instruction Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 3561 Human IL2RG

Swiss-port # P31785 Human Cytokine receptor common subunit gamma

Gene Symbol IL2RG
Gene Full Name interleukin 2 receptor, gamma
Background The protein encoded by this gene is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder. [provided by RefSeq, Mar 2010]
Function Common subunit for the receptors for a variety of interleukins. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15 (PubMed:15123770). [UniProt]
Cellular Localization Membrane; Single-pass type I membrane protein. [UniProt]
Calculated MW 42 kDa