ARG54668
anti-CD150 / SLAM antibody
anti-CD150 / SLAM antibody for ELISA,Immunohistochemistry,Western blot,ICC/IF and Human,Mouse,Rat
Developmental Biology antibody; Immune System antibody; Microbiology and Infectious Disease antibody
Overview
Product Description | Rabbit Polyclonal antibody recognizes CD150 / SLAM |
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Tested Reactivity | Hu, Ms, Rat |
Tested Application | ELISA, ICC/IF, IHC, WB |
Specificity | Two isoforms of SLAMF1 are known to exist; this antibody will recognize both isoforms. SLAMF1 antibody is predicted to not cross-react with other SLAM protein family members. |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | CD150 / SLAM |
Immunogen | Synthetic peptide (15 aa) within aa. 30-80 of Human SLAMF1. |
Conjugation | Un-conjugated |
Alternate Names | Signaling lymphocytic activation molecule; IPO-3; CD150; SLAM; CDw150; CD antigen CD150 |
Application Instructions
Application Suggestion |
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Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
Positive Control | Rat Colon Lysate |
Properties
Form | Liquid |
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Purification | Affinity purification with immunogen. |
Buffer | PBS and 0.02% Sodium azide |
Preservative | 0.02% Sodium azide |
Concentration | 1 mg/ml |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links |
Swiss-port # Q13291 Human Signaling lymphocytic activation molecule Swiss-port # Q9QUM4 Mouse Signaling lymphocytic activation molecule |
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Gene Symbol | SLAMF1 |
Gene Full Name | signaling lymphocytic activation molecule family member 1 |
Background | SLAMF1 Antibody: The signaling lymphocyte-activation molecule family member 1 (SLAMF1) is a novel receptor on T cells that potentiates T cell expansion in a CD28-independent manner. SLAMF1 is predominantly expressed by hematopoietic tissues. Reports suggest that the extracellular domain of SLAMF1 is the receptor for the measles virus and acts as a co-activator on both T and B cells. It is thought to interact with SH2D1A and with PTPN11 via its cytoplasmic domain. Mutations of the SLAM associated gene may be associated with X-linked lympho-proliferative disease (XLP). | |
Research Area | Developmental Biology antibody; Immune System antibody; Microbiology and Infectious Disease antibody |
Calculated MW | 37 kDa |
PTM | Phosphorylated on tyrosine residues by FYN. |