ARG42333
anti-CD157 / BST1 antibody [SY11B5] (FITC)
anti-CD157 / BST1 antibody [SY11B5] (FITC) for Flow cytometry and Primates,Human
Overview
Product Description | FITC-conjugated Mouse Monoclonal antibody [SY11B5] recognizes CD157 / BST1 |
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Tested Reactivity | Hu, NHuPrm |
Tested Application | FACS |
Specificity | The mouse monoclonal antibody SY11B5 recognizes CD157, an approximately 45 kDa GPI-anchored extracellular protein expressed mainly on monocytes, macrophages, granulocytes and bone marrow stromal cells. |
Host | Mouse |
Clonality | Monoclonal |
Clone | SY11B5 |
Isotype | IgG1, kappa |
Target Name | CD157 / BST1 |
Antigen Species | Human |
Immunogen | Human CD157. |
Conjugation | FITC |
Alternate Names | cADPr hydrolase 2; ADP-ribosyl cyclase 2; Cyclic ADP-ribose hydrolase 2; BST-1; Bone marrow stromal antigen 1; CD157; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2; CD antigen CD157; EC 3.2.2.6 |
Application Instructions
Application Suggestion |
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Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
Form | Liquid |
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Purification | Purified |
Buffer | PBS and 15 mM Sodium azide. |
Preservative | 15 mM Sodium azide |
Storage Instruction | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links |
Swiss-port # Q10588 Human ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 |
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Gene Symbol | BST1 |
Gene Full Name | bone marrow stromal cell antigen 1 |
Background | Bone marrow stromal cell antigen-1 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population. [provided by RefSeq, Jul 2008] |
Function | Synthesizes the second messengers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger that elicits calcium release from intracellular stores. May be involved in pre-B-cell growth. [UniProt] |
Cellular Localization | Cell membrane; Lipid-anchor, GPI-anchor. [UniProt] |
Calculated MW | 36 kDa |