ARG58049

anti-CD168 antibody

anti-CD168 antibody for IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human,Mouse

Overview

Product Description Rabbit Polyclonal antibody recognizes CD168
Tested Reactivity Hu, Ms
Tested Application IHC-P, IP, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name CD168
Antigen Species Human
Immunogen Synthetic peptide derived from Human CD168.
Conjugation Un-conjugated
Alternate Names CD168; Intracellular hyaluronic acid-binding protein; IHABP; Receptor for hyaluronan-mediated motility; Hyaluronan mediated motility receptor; RHAMM; CD antigen CD168

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P1:50 - 1:200
IP1:50
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control LNCaP
Observed Size ~ 86 kDa

Properties

Form Liquid
Purification Affinity purified.
Buffer PBS (pH 7.4), 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 15366 Mouse HMMR

GeneID: 3161 Human HMMR

Swiss-port # O75330 Human Hyaluronan mediated motility receptor

Swiss-port # Q00547 Mouse Hyaluronan mediated motility receptor

Gene Symbol HMMR
Gene Full Name hyaluronan-mediated motility receptor (RHAMM)
Background The protein encoded by this gene is involved in cell motility. It is expressed in breast tissue and together with other proteins, it forms a complex with BRCA1 and BRCA2, thus is potentially associated with higher risk of breast cancer. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Dec 2008]
Function Involved in cell motility. When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including PTK2/FAK1 occurs. May also be involved in cellular transformation and metastasis formation, and in regulating extracellular-regulated kinase (ERK) activity. [UniProt]
Cellular Localization Cytoplasm. [UniProt]
Calculated MW 84 kDa