ARG23170
anti-CD1d antibody [1B1]
anti-CD1d antibody [1B1] for IHC-Frozen sections,Flow cytometry,Immunoprecipitation and Mouse
Overview
| Product Description | Rat Monoclonal antibody [1B1] recognizes CD1d Rat anti Mouse CD1d antibody, clone 1B1 recognizes mouse CD1d, a glycoprotein expressed on cortical thymocytes, certain T cell leukemias and various other antigen presenting cells. CD1d binds self and non-self glycolipids and presents them to T cell receptors on natural killer cells. When activated, natural killer cells produce Th1 and Th2 cytokines. |
|---|---|
| Tested Reactivity | Ms |
| Tested Application | FACS, IHC-Fr, IP |
| Host | Rat |
| Clonality | Monoclonal |
| Clone | 1B1 |
| Isotype | IgG2b |
| Target Name | CD1d |
| Antigen Species | Mouse |
| Immunogen | Mouse CD1d cDNA-transfected RMA-S mouse T lymphoma |
| Conjugation | Un-conjugated |
| Alternate Names | CD antigen CD1d; CD1A; R3G1; Antigen-presenting glycoprotein CD1d; R3 |
Application Instructions
| Application Suggestion |
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| Application Note | FACS: Use 10 µl of the suggested working dilution to label 10^6 cells in 100 µl. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified by affinity chromatography. |
| Buffer | PBS and 0.09% Sodium azide. |
| Preservative | 0.09% Sodium azide |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | Cd1d1 |
|---|---|
| Gene Full Name | CD1d1 antigen |
| Background | This gene encodes a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail. [provided by RefSeq, Jul 2008] |
| Function | Antigen-presenting protein that binds self and non-self glycolipids and presents them to T-cell receptors on natural killer T-cells. [UniProt] |
| Calculated MW | 38 kDa |
