ARG42532
anti-CD2 antibody
anti-CD2 antibody for Western blot and Human,Mouse,Rat,Dog,Monkey
Overview
Product Description | Goat Polyclonal antibody recognizes CD2 |
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Tested Reactivity | Hu, Ms, Rat, Dog, Mk |
Tested Application | WB |
Host | Goat |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | CD2 |
Antigen Species | Human |
Immunogen | Recombinant peptide within aa. 300 to the C-terminus of Human CD2. |
Conjugation | Un-conjugated |
Alternate Names | T-cell surface antigen T11/Leu-5; LFA-3 receptor; T-cell surface antigen CD2; SRBC; Erythrocyte receptor; CD antigen CD2; T11; Rosette receptor; LFA-2 |
Application Instructions
Application Suggestion |
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Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
Positive Control | Jurkat | ||||
Observed Size | ~ 50 kDa |
Properties
Form | Liquid |
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Purification | Affinity purification with immunogen. |
Buffer | PBS, 0.05% Sodium azide and 20% Glycerol. |
Preservative | 0.05% Sodium azide |
Stabilizer | 20% Glycerol |
Concentration | 4 mg/ml |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links | |
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Gene Symbol | CD2 |
Gene Full Name | CD2 molecule |
Background | The protein encoded by this gene is a surface antigen found on all peripheral blood T-cells. The encoded protein interacts with LFA3 (CD58) on antigen presenting cells to optimize immune recognition. A locus control region (LCR) has been found in the 3' flanking sequence of this gene. [provided by RefSeq, Jun 2016] |
Function | CD2 interacts with lymphocyte function-associated antigen CD58 (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function. [UniProt] |
Cellular Localization | Cell membrane; Single-pass type I membrane protein. [UniProt] |
Calculated MW | 39 kDa |