ARG22978

anti-CD200 antibody [OX-104]

anti-CD200 antibody [OX-104] for Flow cytometry,IHC-Frozen sections,CyTOF®-candidate and Human

Overview

Product Description Mouse Monoclonal antibody [OX-104] recognizes CD200
Mouse anti Human CD200 antibody, clone OX-104 recognizes the human CD200 cell surface antigen, also known as OX2.CD200 is expressed by a subset of B lymphocytes, some endothelial cells and by neurons. Studies have suggested that the CD200-CD200 ligand system is of importance in the control of macrophage and granulocyte activation.
Tested Reactivity Hu
Tested Application CyTOF®-candidate, FACS, IHC-Fr
Host Mouse
Clonality Monoclonal
Clone OX-104
Isotype IgG1
Target Name CD200
Antigen Species Human
Conjugation Un-conjugated
Alternate Names OX-2; OX-2 membrane glycoprotein; MOX1; MOX2; CD antigen CD200; MRC

Application Instructions

Application Suggestion
Tested Application Dilution
CyTOF®-candidateAssay-dependent
FACSNeat - 1:5
IHC-FrAssay-dependent
Application Note FACS: Use 10 µl of the suggested working dilution to label 10^6 cells in 100 µl.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purification with Protein A.
Buffer PBS and 0.09% Sodium azide
Preservative 0.09% Sodium azide
Concentration 1 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 4345 Human CD200

Swiss-port # P41217 Human OX-2 membrane glycoprotein

Gene Symbol CD200
Gene Full Name CD200 molecule
Background The protein encoded by this gene is a type-1 membrane glycoprotein, which contains two immunoglobulin domains, and thus belongs to the immunoglobulin superfamily. Studies of the related genes in mouse and rat suggest that this gene may regulate myeloid cell activity and delivers an inhibitory signal for the macrophage lineage in diverse tissues. Multiple alternatively spliced transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Function Costimulates T-cell proliferation. May regulate myeloid cell activity in a variety of tissues. [UniProt]
Highlight Related products:
CD200 antibodies; CD200 ELISA Kits; Anti-Mouse IgG secondary antibodies;
Related news:
CyTOF-candidate Antibodies
Calculated MW 31 kDa