ARG22978
anti-CD200 antibody [OX-104]
anti-CD200 antibody [OX-104] for Flow cytometry,IHC-Frozen sections,CyTOF®-candidate and Human
Overview
| Product Description | Mouse Monoclonal antibody [OX-104] recognizes CD200 Mouse anti Human CD200 antibody, clone OX-104 recognizes the human CD200 cell surface antigen, also known as OX2.CD200 is expressed by a subset of B lymphocytes, some endothelial cells and by neurons. Studies have suggested that the CD200-CD200 ligand system is of importance in the control of macrophage and granulocyte activation. |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | CyTOF®-candidate, FACS, IHC-Fr |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | OX-104 |
| Isotype | IgG1 |
| Target Name | CD200 |
| Antigen Species | Human |
| Conjugation | Un-conjugated |
| Alternate Names | OX-2; OX-2 membrane glycoprotein; MOX1; MOX2; CD antigen CD200; MRC |
Application Instructions
| Application Suggestion |
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| Application Note | FACS: Use 10 µl of the suggested working dilution to label 10^6 cells in 100 µl. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A. |
| Buffer | PBS and 0.09% Sodium azide |
| Preservative | 0.09% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | CD200 |
| Gene Full Name | CD200 molecule |
| Background | The protein encoded by this gene is a type-1 membrane glycoprotein, which contains two immunoglobulin domains, and thus belongs to the immunoglobulin superfamily. Studies of the related genes in mouse and rat suggest that this gene may regulate myeloid cell activity and delivers an inhibitory signal for the macrophage lineage in diverse tissues. Multiple alternatively spliced transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Function | Costimulates T-cell proliferation. May regulate myeloid cell activity in a variety of tissues. [UniProt] |
| Highlight | Related products: CD200 antibodies; CD200 ELISA Kits; Anti-Mouse IgG secondary antibodies; Related news: CyTOF-candidate Antibodies |
| Calculated MW | 31 kDa |
