ARG22976

anti-CD200 antibody [OX-90]

anti-CD200 antibody [OX-90] for IHC-Frozen sections,ELISA,Flow cytometry and Mouse

Overview

Product Description Rat Monoclonal antibody [OX-90] recognizes CD200
Rat anti Mouse CD200 antibody, clone OX-90 recognizes the mouse CD200 cell surface antigen, also known as OX2.CD200 is expressed by splenic B lymphocytes, follicular dendritic cells, splenic endothelium and by neurons.Studies have suggested that the CD200 - CD200 ligand system is of importance in the control of macrophage and granulocyte activation.
Tested Reactivity Ms
Tested Application ELISA, FACS, IHC-Fr
Host Rat
Clonality Monoclonal
Clone OX-90
Isotype IgG2a
Target Name CD200
Antigen Species Mouse
Immunogen Mouse CD200-rat CD4 fusion protein.
Conjugation Un-conjugated
Alternate Names OX-2; OX-2 membrane glycoprotein; MOX1; MOX2; CD antigen CD200; MRC

Application Instructions

Application Suggestion
Tested Application Dilution
ELISAAssay-dependent
FACSAssay-dependent
IHC-FrAssay-dependent
Application Note FACS: Use 10 µl of the suggested working dilution to label 10^6 cells in 100 µl.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purification with Protein G.
Buffer PBS and 0.09% Sodium azide
Preservative 0.09% Sodium azide
Concentration 1 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Gene Symbol Cd200
Gene Full Name CD200 antigen
Background The protein encoded by this gene is a type-1 membrane glycoprotein, which contains two immunoglobulin domains, and thus belongs to the immunoglobulin superfamily. Studies of the related genes in mouse and rat suggest that this gene may regulate myeloid cell activity and delivers an inhibitory signal for the macrophage lineage in diverse tissues. Multiple alternatively spliced transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Function Costimulates T-cell proliferation. May regulate myeloid cell activity in a variety of tissues. [UniProt]
Calculated MW 31 kDa