ARG23475
anti-CD21 antibody [CC51] (FITC)
anti-CD21 antibody [CC51] (FITC) for Flow cytometry and Bovine,Pig
Overview
Product Description | FITC-conjugated Mouse Monoclonal antibody [CC51] recognizes CD21 Mouse anti Bovine CD21 monoclonal antibody, clone CC51 recognizes the bovine homologue of the human CD21 cell surface antigen, a 145 kDa single pass type I membrane glycoprotein containing multiple sushi domains. CD21 is also known as complement receptor type 2 (CR2). In cattle CD21 expression is restricted to B-cells (Naessens et al. 1990). CD21 may be expressed on B-cells as either a long or a short form (Pringle et al. 2012). Mouse anti Bovine CD21, clone CC51 demonstrates cross reactivity with porcine and provides a reliable marker for porcine B-Cells (Sinkora et. al. 2013). |
---|---|
Tested Reactivity | Bov, Pig |
Tested Application | FACS |
Host | Mouse |
Clonality | Monoclonal |
Clone | CC51 |
Isotype | IgG2b |
Target Name | CD21 |
Antigen Species | Bovine |
Immunogen | Bovine (Friesian cattle) mesenteric lymph node cells |
Conjugation | FITC |
Alternate Names | Cr2; Complement C3d receptor; C3DR; CD21; CD antigen CD21; Complement receptor type 2; SLEB9; CR; CVID7; Epstein-Barr virus receptor; EBV receptor |
Application Instructions
Application Suggestion |
|
||||
---|---|---|---|---|---|
Application Note | FACS: Use 10 µl of the suggested working dilution to label 10^6 cells in 100 µl * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
Form | Liquid |
---|---|
Purification | Purification with Protein A. |
Buffer | PBS, 0.09% Sodium azide and 1% BSA. |
Preservative | 0.09% Sodium azide |
Stabilizer | 1% BSA |
Concentration | 0.1 mg/ml |
Storage Instruction | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Gene Symbol | CR2 |
---|---|
Gene Full Name | complement component (3d/Epstein Barr virus) receptor 2 |
Background | This gene encodes a membrane protein, which functions as a receptor for Epstein-Barr virus (EBV) binding on B and T lymphocytes. Genetic variations in this gene are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009] |
Function | Receptor for complement C3Dd, for the Epstein-Barr virus on human B-cells and T-cells and for HNRPU. Participates in B lymphocytes activation. [UniProt] |
Calculated MW | 113 kDa |