ARG42361

anti-CD21 antibody [LT21] (PerCP)

anti-CD21 antibody [LT21] (PerCP) for Flow cytometry and Pig,Human,Dog,Cow

Overview

Product Description PerCP-conjugated Mouse Monoclonal antibody [LT21] recognizes CD21
Tested Reactivity Hu, Cow, Dog, Pig
Tested Application FACS
Specificity The antibody LT21 reacts with an extracellular epitope of CD21 (CR2), a 145 kDa transmembrane glycoprotein (complement C3d receptor - C3dR) expressed on B lymphocytes, follicular dendritic cells, some epithelial cells and a subsets of T lymphocytes. It is not expressed on immature B cells.
Host Mouse
Clonality Monoclonal
Clone LT21
Isotype IgG1
Target Name CD21
Antigen Species Human
Immunogen IM9 Human B-lymphoblastoid cell line.
Conjugation PerCP
Alternate Names Cr2; Complement C3d receptor; C3DR; CD21; CD antigen CD21; Complement receptor type 2; SLEB9; CR; CVID7; Epstein-Barr virus receptor; EBV receptor

Application Instructions

Application Suggestion
Tested Application Dilution
FACS10 µl / 100 µl of whole blood or 10^6 cells
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified
Buffer PBS and 15 mM Sodium azide.
Preservative 15 mM Sodium azide
Storage Instruction Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 1380 Human CR2

Swiss-port # P20023 Human Complement receptor type 2

Gene Symbol CR2
Gene Full Name complement component (3d/Epstein Barr virus) receptor 2
Background This gene encodes a membrane protein, which functions as a receptor for Epstein-Barr virus (EBV) binding on B and T lymphocytes. Genetic variations in this gene are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
Function Receptor for complement C3, for the Epstein-Barr virus on human B-cells and T-cells and for HNRNPU (PubMed:7753047). Participates in B lymphocytes activation (PubMed:7753047).

(Microbial infection) Acts as a receptor for Epstein-Barr virus. [UniProt]
Cellular Localization Membrane; Single-pass type I membrane protein. [UniProt]
Calculated MW 113 kDa