ARG58719

anti-CD223 / LAG3 antibody

anti-CD223 / LAG3 antibody for Western blot and Human,Mouse

Overview

Product Description Rabbit Polyclonal antibody recognizes CD223 / LAG3
Tested Reactivity Hu, Ms
Tested Application WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name CD223 / LAG3
Antigen Species Human
Immunogen Recombinant fusion protein corresponding to aa. 29-170 of Human LAG3 (NP_002277.4).
Conjugation Un-conjugated
Alternate Names CD antigen CD223; CD223; Protein FDC; Lymphocyte activation gene 3 protein; LAG-3

Application Instructions

Application Suggestion
Tested Application Dilution
WB1:1000 - 1:4000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control Raji
Observed Size 72 kDa

Properties

Form Liquid
Purification Affinity purified.
Buffer PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 16768 Mouse LAG3

GeneID: 3902 Human LAG3

Swiss-port # P18627 Human Lymphocyte activation gene 3 protein

Swiss-port # Q61790 Mouse Lymphocyte activation gene 3 protein

Gene Symbol LAG3
Gene Full Name lymphocyte-activation gene 3
Background Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. [provided by RefSeq, Jul 2008]
Function Involved in lymphocyte activation. Binds to HLA class-II antigens. [UniProt]
Cellular Localization Membrane, Single-pass type I membrane protein. [UniProt]
Calculated MW 57 kDa