ARG20878
anti-CD23 antibody [2G8] (PE-Cyanine 7)
anti-CD23 antibody [2G8] (PE-Cyanine 7) for Flow cytometry,IHC-Frozen sections and Mouse
Overview
| Product Description | PE-Cyanine 7-conjugated Rat Monoclonal antibody [2G8] recognizes CD23 |
|---|---|
| Tested Reactivity | Ms |
| Tested Application | FACS, IHC-Fr |
| Specificity | Mouse CD23. |
| Host | Rat |
| Clonality | Monoclonal |
| Clone | 2G8 |
| Isotype | IgG2a, kappa |
| Target Name | CD23 |
| Antigen Species | Mouse |
| Immunogen | FcεR isolated from B cell lymphoma cell line M12.4.5 |
| Conjugation | PE-Cyanine 7 |
| Alternate Names | CD23A; BLAST-2; Lymphocyte IgE receptor; CLEC4J; Immunoglobulin E-binding factor; CD23; IGEBF; Fc-epsilon-RII; CD antigen CD23; FCE2; Low affinity immunoglobulin epsilon Fc receptor; C-type lectin domain family 4 member J |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Buffer | PBS, 0.1% Sodium azide and Sucrose. |
| Preservative | 0.1% Sodium azide |
| Stabilizer | Sucrose |
| Concentration | 0.1 mg/ml |
| Storage Instruction | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | FCER2 |
|---|---|
| Gene Full Name | Fc receptor, IgE, low affinity II, alpha polypeptide |
| Background | The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011] |
| Function | Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen). [UniProt] |
| Calculated MW | 36 kDa |
| PTM | N- and O-glycosylated. The secreted form sCD23 is produced by ADAM10-mediated ectodomain shedding. |
