ARG23889
anti-CD23 antibody [Tu1]
anti-CD23 antibody [Tu1] for Blocking,Flow cytometry,ICC/IF,IHC-Frozen sections,Western blot and Human
Overview
| Product Description | Mouse Monoclonal antibody [Tü1] recognizes CD23 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | BL, FACS, ICC/IF, IHC-Fr, WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | Tü1 |
| Isotype | IgG3, kappa |
| Target Name | CD23 |
| Antigen Species | Human |
| Immunogen | Purified Human tonsil lymphocytes (KR3598 cells). |
| Conjugation | Un-conjugated |
| Alternate Names | CD23A; BLAST-2; Lymphocyte IgE receptor; CLEC4J; Immunoglobulin E-binding factor; CD23; IGEBF; Fc-epsilon-RII; CD antigen CD23; FCE2; Low affinity immunoglobulin epsilon Fc receptor; C-type lectin domain family 4 member J |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | BBS (pH 8.2) |
| Concentration | 0.1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P06734 Human Low affinity immunoglobulin epsilon Fc receptor |
|---|---|
| Gene Symbol | FCER2 |
| Gene Full Name | Fc fragment of IgE, low affinity II, receptor for (CD23) |
| Background | The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011] |
| Function | Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen). [UniProt] |
| Cellular Localization | Cell membrane; Single-pass type II membrane protein. Cell membrane; Lipid-anchor. Secreted. Note=Also exists as a soluble excreted form, sCD23. [UniProt] |
| Calculated MW | 36 kDa |
| PTM | N- and O-glycosylated. The secreted form sCD23 is produced by ADAM10-mediated ectodomain shedding. [UniProt] |
