ARG22087

anti-CD24 antibody [30-F1] (FITC)

anti-CD24 antibody [30-F1] (FITC) for Flow cytometry and Mouse

Overview

Product Description FITC-conjugated Rat Monoclonal antibody [30-F1] recognizes CD24
Tested Reactivity Ms
Tested Application FACS
Specificity Mouse CD24
Host Rat
Clonality Monoclonal
Clone 30-F1
Isotype IgG2c, kappa
Target Name CD24
Antigen Species Mouse
Immunogen Mouse thymus or spleen
Conjugation FITC
Alternate Names Signal transducer CD24; CD antigen CD24; CD24A; Small cell lung carcinoma cluster 4 antigen

Application Instructions

Application Suggestion
Tested Application Dilution
FACS< 2 µg/10^6 cells
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Buffer PBS and 0.1% Sodium azide.
Preservative 0.1% Sodium azide
Concentration 0.5 mg/ml
Storage Instruction Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Gene Symbol CD24
Gene Full Name CD24a antigen
Background This gene encodes a sialoglycoprotein that is expressed on mature granulocytes and B cells and modulates growth and differentiation signals to these cells. The precursor protein is cleaved to a short 32 amino acid mature peptide which is anchored via a glycosyl phosphatidylinositol (GPI) link to the cell surface. This gene was missing from previous genome assemblies, but is properly located on chromosome 6. Non-transcribed pseudogenes have been designated on chromosomes 1, 15, 20, and Y. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
Function Modulates B-cell activation responses. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells. [UniProt]
Calculated MW 8 kDa
PTM Extensively O-glycosylated.