ARG22087
anti-CD24 antibody [30-F1] (FITC)
anti-CD24 antibody [30-F1] (FITC) for Flow cytometry and Mouse
Overview
Product Description | FITC-conjugated Rat Monoclonal antibody [30-F1] recognizes CD24 |
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Tested Reactivity | Ms |
Tested Application | FACS |
Specificity | Mouse CD24 |
Host | Rat |
Clonality | Monoclonal |
Clone | 30-F1 |
Isotype | IgG2c, kappa |
Target Name | CD24 |
Antigen Species | Mouse |
Immunogen | Mouse thymus or spleen |
Conjugation | FITC |
Alternate Names | Signal transducer CD24; CD antigen CD24; CD24A; Small cell lung carcinoma cluster 4 antigen |
Application Instructions
Application Suggestion |
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Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
Form | Liquid |
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Buffer | PBS and 0.1% Sodium azide. |
Preservative | 0.1% Sodium azide |
Concentration | 0.5 mg/ml |
Storage Instruction | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Gene Symbol | CD24 |
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Gene Full Name | CD24a antigen |
Background | This gene encodes a sialoglycoprotein that is expressed on mature granulocytes and B cells and modulates growth and differentiation signals to these cells. The precursor protein is cleaved to a short 32 amino acid mature peptide which is anchored via a glycosyl phosphatidylinositol (GPI) link to the cell surface. This gene was missing from previous genome assemblies, but is properly located on chromosome 6. Non-transcribed pseudogenes have been designated on chromosomes 1, 15, 20, and Y. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014] |
Function | Modulates B-cell activation responses. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells. [UniProt] |
Calculated MW | 8 kDa |
PTM | Extensively O-glycosylated. |