ARG23986

anti-CD268 / BAFF R antibody [2C4]

anti-CD268 / BAFF R antibody [2C4] for IHC-Formalin-fixed paraffin-embedded sections,IHC-Frozen sections,Flow cytometry and Chicken,Turkey,Duck

Overview

Product Description Mouse Monoclonal antibody [2C4] recognizes CD268 / BAFF R
Tested Reactivity Chk, Duck, Turkey
Tested Application FACS, IHC-Fr, IHC-P
Host Mouse
Clonality Monoclonal
Clone 2C4
Isotype IgG1
Target Name CD268 / BAFF R
Antigen Species Chicken
Immunogen Chicken BAFF R transfected HEK293 cells.
Conjugation Un-conjugated
Alternate Names CD antigen CD268; BROMIX; BAFF-R; CD268; Tumor necrosis factor receptor superfamily member 13C; BAFF receptor; BAFFR; B-cell-activating factor receptor; prolixin; CVID4; BLyS receptor 3

Application Instructions

Application Suggestion
Tested Application Dilution
FACSAssay-dependent
IHC-FrAssay-dependent
IHC-PAssay-dependent
Application Note FACS: Use 10 µl of the suggested working dilution to label 10^6 cells in 100 µl.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purification with Protein G.
Buffer PBS and 0.01% Sodium azide.
Preservative 0.01% Sodium azide
Concentration 1 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Gene Symbol TNFRSF13C
Gene Full Name tumor necrosis factor receptor superfamily, member 13C
Background B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival. [provided by RefSeq, Jul 2008]
Function B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Promotes the survival of mature B-cells and the B-cell response. [UniProt]
Cellular Localization Membrane; Single-pass type III membrane protein. [UniProt]
Calculated MW 19 kDa