ARG55520

anti-CD272 / BTLA antibody

anti-CD272 / BTLA antibody for Western blot and Mouse,Rat

Immune System antibody

Overview

Product Description Rabbit Polyclonal antibody recognizes CD272 / BTLA
Tested Reactivity Ms, Rat
Predict Reactivity Hu
Tested Application WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name CD272 / BTLA
Antigen Species Human
Immunogen Recombinant protein of Human BTLA
Conjugation Un-conjugated
Alternate Names CD antigen CD272; BTLA1; B- and T-lymphocyte-associated protein; B- and T-lymphocyte attenuator; CD272

Application Instructions

Application Suggestion
Tested Application Dilution
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control Rat lung
Observed Size ~ 33 kDa

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 208154 Mouse BTLA

GeneID: 407756 Rat BTLA

Swiss-port # Q6PNM1 Rat B- and T-lymphocyte attenuator

Swiss-port # Q7TSA3 Mouse B- and T-lymphocyte attenuator

Gene Symbol BTLA
Gene Full Name B and T lymphocyte associated
Background This gene encodes a member of the immunoglobulin superfamily. The encoded protein contains a single immunoglobulin (Ig) domain and is a receptor that relays inhibitory signals to suppress the immune response. Alternative splicing results in multiple transcript variants. Polymorphisms in this gene have been associated with an increased risk of rheumatoid arthritis. [provided by RefSeq, Aug 2011]
Function Lymphocyte inhibitory receptor which inhibits lymphocytes during immune response. [UniProt]
Research Area Immune System antibody
Calculated MW 33 kDa
PTM Phosphorylated on Tyr residues by TNFRSF14 and by antigen receptors cross-linking, both inducing association with PTPN6 and PTPN11.
N-glycosylated.