ARG52539
anti-CD276 / B7-H3 antibody [SP206]
anti-CD276 / B7-H3 antibody [SP206] for IHC-Formalin-fixed paraffin-embedded sections,Western blot,Flow cytometry and Human
Cancer antibody; Developmental Biology antibody; Immune System antibody
Overview
| Product Description | Rabbit Monoclonal antibody [SP206] recognizes CD276 / B7-H3 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | FACS, IHC-P, WB |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone | SP206 |
| Isotype | IgG |
| Target Name | CD276 / B7-H3 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide derived from human B7-H3 protein. |
| Conjugation | Un-conjugated |
| Alternate Names | B7-H3; B7 homolog 3; B7H3; 4Ig-B7-H3; B7RP-2; Costimulatory molecule; CD antigen CD276; CD276 antigen |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Positive Control | Tonsil, 293T Cell Lysate |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified by protein A/G |
| Buffer | PBS (pH 7.6), 1% BSA and < 0.1% Sodium azide |
| Preservative | < 0.1% Sodium azide |
| Stabilizer | 1% BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Background | CD276 (also known as B7-H3) is a membrane protein that participates in the regulation of T cell-mediated immune response. It is expressed widely in dendritic cells, some epithelial cells, trophoblast cells, Hofbauer cells of the placenta, activated B and T cells, NK cells, and monocytes. CD276 is also expressed by some solid tumors such as melanoma, prostate cancer, and pancreatic cancer. |
| Cellular Localization | Membrane |
| Highlight | Related products: CD276 antibodies; Anti-Rabbit IgG secondary antibodies; Related news: New PD-1 ELISA Kit, excellent for preclinical studies or pharmatheutical development Why anti-PD-1/PD-L1 therapy doesn’t work? Time to fight cancer by NK cells Examining CTL/NK-mediated cytotoxicity by ELISA |
| Research Area | Cancer antibody; Developmental Biology antibody; Immune System antibody |
| Calculated MW | 57 kDa |
