ARG21154
anti-CD3 antibody [CT-3] (PE-Cyanine 5)
anti-CD3 antibody [CT-3] (PE-Cyanine 5) for Flow cytometry,IHC-Frozen sections,IHC-Formalin-fixed paraffin-embedded sections and Chicken
Overview
| Product Description | PE-Cyanine 5-conjugated Mouse Monoclonal antibody [CT-3] recognizes CD3 |
|---|---|
| Tested Reactivity | Chk |
| Tested Application | FACS, IHC-Fr, IHC-P |
| Specificity | Chicken CD3. The clone CT-3 recognizes a complex of at least three polypeptides of Mr 20, 19, and 17 kDa (two of which are N-glycosylated) on chicken T cells. The antibody also coprecipitates a polypeptide of 90 kDa from digitonin solubilized T cell lysates, which can be reduced to two polypeptides of Mr 50 and 40 kDa. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | CT-3 |
| Isotype | IgG1, kappa |
| Target Name | CD3 |
| Antigen Species | Chicken |
| Immunogen | Chicken thymocytes and Ig- blood mononuclear cells |
| Conjugation | PE-Cyanine 5 |
| Alternate Names | T-cell receptor T3 delta chain; T3D; IMD19; CD3-DELTA; CD antigen CD3d; T-cell surface glycoprotein CD3 delta chain |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Buffer | PBS, 0.1% Sodium azide and Sucrose. |
| Preservative | 0.1% Sodium azide |
| Stabilizer | Sucrose |
| Concentration | 0.1 mg/ml |
| Storage Instruction | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | CD3D |
|---|---|
| Gene Full Name | CD3d molecule, delta (CD3-TCR complex) |
| Background | The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined. [provided by RefSeq, Feb 2009] |
| Function | The CD3 complex mediates signal transduction. [UniProt] |
| Highlight | Related products: CD3 antibodies; CD3 ELISA Kits; CD3 Duos / Panels; CD3 recombinant proteins; Anti-Mouse IgG secondary antibodies; Related news: New antibody panels and duos for Tumor immune microenvironment Tumor-Infiltrating Lymphocytes (TILs) Exploring Antiviral Immune Response |
| Calculated MW | 19 kDa |
