ARG22015
anti-CD30 antibody [mCD30.1] (Biotin)
anti-CD30 antibody [mCD30.1] (Biotin) for Flow cytometry,Blocking and Mouse
Overview
| Product Description | Biotin-conjugated Hamster Monoclonal antibody [mCD30.1] recognizes CD30 |
|---|---|
| Tested Reactivity | Ms |
| Tested Application | BL, FACS |
| Specificity | Mouse CD30 |
| Host | Hamster |
| Clonality | Monoclonal |
| Clone | mCD30.1 |
| Isotype | IgG1 |
| Target Name | CD30 |
| Antigen Species | Mouse |
| Immunogen | Mouse CD30-Mouse IgG1 fusion protein |
| Conjugation | Biotin |
| Alternate Names | Tumor necrosis factor receptor superfamily member 8; Ki-1 antigen; CD30; Ki-1; Lymphocyte activation antigen CD30; CD antigen CD30; D1S166E; CD30L receptor |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Buffer | PBS and 0.1% Sodium azide. |
| Preservative | 0.1% Sodium azide |
| Concentration | 0.5 mg/ml |
| Storage Instruction | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q60846 Mouse Tumor necrosis factor receptor superfamily member 8 |
|---|---|
| Gene Symbol | TNFRSF8 |
| Gene Full Name | tumor necrosis factor receptor superfamily, member 8 |
| Background | CD30 is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] |
| Function | CD30 is a receptor for TNFSF8/CD30L (PubMed:8391931). May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B (PubMed:8999898). [UniProt] |
| Calculated MW | 64 kDa |
| PTM | Phosphorylated on serine and tyrosine residues. |
