ARG54303
anti-CD300e antibody [UP-H2] (APC)
anti-CD300e antibody [UP-H2] (APC) for Flow cytometry and Human
Immune System antibody
Overview
| Product Description | APC-conjugated Mouse Monoclonal antibody [UP-H2] recognizes CD300e |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | FACS |
| Specificity | The clone UP-H2 recognizes CD300e / IREM-2, a 32 kDa glycoprotein expressed by mature monocytes and peripheral blood myeloid dendritic cells. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | UP-H2 |
| Isotype | IgG1 |
| Target Name | CD300e |
| Immunogen | CD300e-HA-transfected cells |
| Conjugation | APC |
| Alternate Names | Poly-Ig receptor 2; Immune receptor expressed on myeloid cells 2; IREM-2; CD300LE; CMRF35-A5; CD antigen CD300e; CLM2; IREM2; CMRF35-like molecule 2; PIgR2; CLM-2; Polymeric immunoglobulin receptor 2; PIgR-2; CD300 antigen-like family member E |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification Note | The purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary. |
| Buffer | PBS, 15 mM Sodium azide and 0.2% (w/v) high-grade protease free BSA |
| Preservative | 15 mM Sodium azide |
| Stabilizer | 0.2% (w/v) high-grade protease free BSA |
| Storage Instruction | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | CD300E |
| Gene Full Name | CD300e molecule |
| Background | CD300e / IREM-2 (immune receptor expressed by myeloid cells 2), also known as CLM2 or LMIR6, is a monomeric transmembrane glycoprotein with a single extracellular immunoglobulin-like domain. Intracellularly it associates with DAP-12, an ITAM-containing adaptor molecule. CD300e is expressed on mature monocytes and peripheral blood myeloid dendritic cells. Its crosslinking leads to release of pro-inflammatory cytokines, and increased expression of activation markers. |
| Function | Probably acts as an activating receptor. [UniProt] |
| Research Area | Immune System antibody |
| Calculated MW | 23 kDa |
| PTM | N-glycosylated. |
Clone References
Molecular characterization of a novel immune receptor restricted to the monocytic lineage.
