ARG65188

anti-CD305 / LAIR1 antibody

anti-CD305 / LAIR1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human

Immune System antibody

Overview

Product Description Goat Polyclonal antibody recognizes CD305 / LAIR1
Tested Reactivity Hu
Tested Application IHC-P, WB
Specificity This antibody is expected to recognize both isoforms (NP_002278.1; NP_068352.1).
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name CD305 / LAIR1
Antigen Species Human
Immunogen C-NDTEDVSQASPSE
Conjugation Un-conjugated
Alternate Names LAIR-1; hLAIR1; CD305; CD antigen CD305; Leukocyte-associated immunoglobulin-like receptor 1

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P3 - 5 µg/ml
WB1 - 3 µg/ml
Application Note WB: Recommend incubate at RT for 1h.
IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 3903 Human LAIR1

Swiss-port # Q6GTX8 Human Leukocyte-associated immunoglobulin-like receptor 1

Background The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including NK cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. [provided by RefSeq, Jul 2008]
Research Area Immune System antibody
Calculated MW 31 kDa
PTM Phosphorylation at Tyr-251 and Tyr-281 activates it. May be phosphorylated by LCK.
N-glycosylated.