ARG63774

anti-CD32B antibody

anti-CD32B antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human

Developmental Biology antibody; Immune System antibody

Overview

Product Description Goat Polyclonal antibody recognizes CD32B
Tested Reactivity Hu
Tested Application IHC-P, WB
Specificity This antibody is expected to recognise all reported isoforms (NP_001002273.1; NP_001002274.1; NP_001002275.1; NP_003992.3; NP_001177757.1).
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name CD32B
Antigen Species Human
Immunogen C-PDALEEPDDQNRI
Conjugation Un-conjugated
Alternate Names Fc-gamma-RIIc; Fc-gamma RII-c; CD32; CD antigen CD32; CD32B; IgG Fc receptor II-c; Low affinity immunoglobulin gamma Fc region receptor II-c; FCG2; IGFR2; FcRII-c; FCGR2; CDw32

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-PAssay - dependent
WB0.3 - 1 µg/ml
Application Note WB: Recommend incubate at RT for 1h.
IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 2213 Human FCGR2B

Swiss-port # P31994 Human Low affinity immunoglobulin gamma Fc region receptor II-b

Background The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
Research Area Developmental Biology antibody; Immune System antibody
Calculated MW 36 kDa
PTM Phosphorylated by the SRC-type Tyr-kinases LYN and BLK.