ARG53836

anti-CD361 / EVI2B antibody [MEM-216] (PE)

anti-CD361 / EVI2B antibody [MEM-216] (PE) for Flow cytometry and Human

Cell Biology and Cellular Response antibody

Overview

Product Description

PE-conjugated Mouse Monoclonal antibody [MEM-216] recognizes CD361

Tested Reactivity Hu
Tested Application FACS
Specificity The clone MEM-216 recognizes CD361 / EVI2B, almost uncharacterized type I transmembrane protein with broad leukocyte expression, mostly in myeloid and B cells.
HLDA IX.; WS Code 263
Host Mouse
Clonality Monoclonal
Clone MEM-216
Isotype IgG1
Target Name CD361 / EVI2B
Antigen Species Human
Immunogen Raji cells_x000D_
Conjugation PE
Alternate Names CD361; EVDB; EVI-2B; CD antigen CD361; Protein EVI2B; Ecotropic viral integration site 2B protein homolog; D17S376

Application Instructions

Application Suggestion
Tested Application Dilution
FACS20 µl / 10^6 cells
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Note The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
Buffer PBS, 15 mM Sodium azide and 0.2% (w/v) high-grade protease free BSA
Preservative 15 mM Sodium azide
Stabilizer 0.2% (w/v) high-grade protease free BSA
Storage Instruction Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 2124 Human EVI2B

Swiss-port # P34910 Human Protein EVI2B

Gene Symbol EVI2B
Gene Full Name ecotropic viral integration site 2B
Background CD361, also known as EVI2B (Ecotropic Viral Integration site 2B) or EVDB, is a poorly characterized type I transmembrane protein, expressed from one of three genes embedded in intron 27b of the neurofibromatosis type 1 (NF1) gene. The DNA strand that is transcribed to produce CD361 is the complementary one to the strand encoding NF1. Murine homolog to human CD361 is associated with ecotropic viral insertions, which have been implicated in the expression of murine myeloid leukemias. CD361 has been also reported to be involved in melanocyte and keratinocyte differentiation. However, it is expressed mainly in peripheral blood and bone marrow.
Research Area Cell Biology and Cellular Response antibody
Calculated MW 49 kDa